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Forbes’ list of The World’s 100 Most Powerful Women 2016 celebrates the smartest and toughest female business leaders, entrepreneurs, investors, scientists, philanthropists and CEOs making their mark in the world today. Here are the 10 most powerful women in the world:

1. Angela Merkel

Title: Chancellor, Germany

2. Hillary Clinton

Title: Presidential candidate, United States

3. Janet Yellen

Title: Chair, Federal Reserve, Washington, United States

4. Melinda Gates

Title: Cochair, Bill & Melinda Gates Foundation

5. Mary Barra

Title: CEO, General Motors

6. Christine Lagarde

Title: Managing director, International Monetary Fund

7. Sheryl Sandberg

Title: COO, Facebook

8. Susan Wojcicki

Title: CEO, YouTube, Google

9. Meg Whitman

Title: CEO, Hewlett-Packard

10. Ana Patricia Botín

Title: Chair, Santander Group, Banco Santander